Dr. Peña research interest is focused on the study GPCR signaling, particularly the parathyroid hormone receptor (PTHR). Employing optical techniques (such as FRET, live cell imaging, etc) she studies different aspects of PTHR biology. In particular, Dr. Peña’s research is focused on understanding how location of cAMP signal (cell surface vs endosomes) affects biological aspects of PTHR function, including vitamin D synthesis in the kidney. In addition, Dr. Peña is interested in understanding how membrane lipids affect PTHR function and signaling, by regulating recruitment of beta arrestins to the receptor.