Dr. Sigal received a degree in physics from the Universidad Nacional Autónoma de México in México City, a masters in aerospace engineering from the University of Toronto in Canada, and a Ph.D. in Mechanical Engineering also from the University of Toronto in Canada. Dr. Sigal has dedicated his scientific career to the study of biomechanics-related diseases of the eye, and to glaucoma in particular. In October 2010, he joined the University of Pittsburgh and founded the Laboratory of Ocular Biomechanics. He pioneered methods to study the eye using computational modeling to understand why some individuals develop glaucoma while others do not.  His laboratory also works developing tools to study the architecture of the eye and how this impacts vision health. He has published over 100 peer-reviewed manuscripts and is coauthor on over 300 conference abstracts and presentations. The laboratory has received support from the National Institutes of Health, the Canadian Institutes of Health Research, The Glaucoma Research Foundation and others.