Dr. Abebe's collaborative research focuses on design, conduct, and analysis of multicenter, randomized, controlled trials (RCTs), namely in polycystic kidney disease (PKD). He leads the data coordinating centers (DCC)for the TAME-PKD clinical trial assessing the safety and tolerability of metformin in PKD; and the STERIO-SCD trial, which is evaluating safety and preliminary efficacy of riociguat in patients with sickle cell disease.

Additionally, he leads the statistical and data management cores for clinical trials in gestational diabetes (GDM2 Study; PI: Davis), heart failure and depression (Hopeful Heart; PI: Rollman), and HIV (DIPY and DC-04 studies; PI: Riddler). Most recently, we was the DCC PI for the HALT-PKD Network, which comprised two multicenter RCTs evaluating the impact of hypertensive medications and blood pressure control on PKD.

Dr. Abebe is the founding director of the Center for Clinical Trials & Data Coordination, created to standardize the design, conduct, and analysis of RCTs.